With a continued focus on customers, BioDiscovery moves from a sales and support departmental structure to a holistic team filled with Customer Success Managers.
Cedar Sinai Medical Center in Los Angeles, CA has filed a patent for a method for prognosticating patient survival based on the ZEB1 gene. The application also describes methods for selecting therapies based on analysis of ZEB1 and several other genes.
More and more plant and animal genomes are being sequenced and mapped - ANY organism with a mapped genome can be analyzed for copy number analysis using Nexus Copy Number.
Sometimes a wave-like pattern is seen in the probe distribution across chromosomes. This artifact can affect the accuracy of calls. Systematic correction based on GC content of the probe sequence and its neighborhood can be applied to minimize this problem.
You already know that Nexus Copy Number is a versatile software for genomic data analysis that can load and process data from different technologies (arrays, NGS), manufacturers (Agilent, Affymetrix, Illumina…), and modalities (copy number, sequence variants, gene expression, methylation).
CoNIFER can be used to discover CNVs that might be missed by standard practices. Look at our considerations when evaluating the CoNIFER algorithm.
Take a look at how Nexus Copy Number handles the different “Raw Data” and the three steps to analyzing the data.
Cancer samples usually contain a mixture of tumor and normal cells. Take a look at this formula for calculating a one-copy loss event.