Events

BioDiscovery attends and sponsors numerous events throughout the year. This is an excellent opportunity to view the latest product demonstrations and to have your questions answer by our knowledgeable staff. Please visit us at these upcoming events:

Upcoming

Webinar: Copy Number Analysis of Head & Neck Cancer and Association with HPV Status Using Nexus Copy Number and Empire Genomics BAC Arrays
May 19, 7:30 AM PDT / 10:30 AM EDT / 3:30 PM GMT
May 22, 11:00 AM PDT / 2:00 PM EDT

Seminar: Array-based Copy Number Analysis with Nexus Copy Number
May 20, 2:00 PM EST, Duke Center for Human Genetics, Durham, NC

Webinar: Array-based Copy Number Analysis of Breast Cancer (from FFPE Derived Samples)
Wednesday, May 28th, 10:30 AM Eastern Australia time zone / Tuesday May 27th 5:30 PM PDT USA

Conference: European Human Genetics Conference (ESHG 2008)
May 31 – June 2, Barcelona, Spain

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Webinars

Copy Number Analysis of Head & Neck Cancer and Association with HPV Status Using Nexus Copy Number and Empire Genomics BAC Arrays

In this webinar we will show how Nexus Copy Number Professional was used to analyze aCGH data from Head and Neck Carcinoma samples processed on Empire Genomics' Human ACCUArray platform. Head and neck cancers account for 3-5% of all cancers in the US. Tobacco and alcohol are the most common risk factors. Mutations in p53 and HPV are some other factors implicated in certain head and neck cancers. The samples used in this study consisted of 53 fresh frozen tissues and eight FFPE samples forming a set of 61 samples in. Using Nexus Copy Number Professional, we will demonstrate how the raw data can be transformed into biological insights in a few minutes. We will show how we have been able to identify regions that have differences in copy number between HPV positive and HPV negative samples and how the aberration profile generated correlated very well with previously published results. We will demonstrate how we were able to integrate GO annotations to discover that one of the highly ranked GO Biological Processes is the cell cycle checkpoint process. Clustering of samples based on aberrations and association with survival will also be covered.

Date: Monday, May 19, 2008
Time: 7:30 AM - 8:30 AM PDT / 10:30 AM - 11:30 AM EDT / 3:30 PM - 4:30 PM GMT
Registration Link: https://www2.gotomeeting.com/register/905425256

Date: Thursday, May 22, 2008
Time: 11:00 AM - 12:00 PM PDT / 2:00 PM - 3:00 PM EDT
Registration link: https://www2.gotomeeting.com/register/697356005

*Please note that you must use your organizational e-mail address on the registration form. Those entering free e-mail accounts such as yahoo, gmail, etc. will be denied registration.

For more information on Nexus Copy Number, please visit http://www.biodiscovery.com/index/nexus.

For more information on Empire Genomics' high resolution CGH arrays, please visit http://www.empiregenomics.com/site/products_arrays.php


Array-based Copy Number Analysis of Breast Cancer (from FFPE Derived Samples)

In this presentation we will demonstrate the utility and efficiency of BioDiscovery’s Nexus Copy Number by analyzing a set of Breast Cancer samples (extracted from FFPE source and hybridized on Agilent 244K arrays). We will show Nexus’ ability to integrate phenotypic data as well as gene expression data by looking at the correlation of gene expression patterns from Her2 positive samples and overlay those with copy number gain regions obtained using CGH analysis. We will then show how genome-wide clustering can identify different groupings of samples based on copy number profiles and then show survival analysis on resulting clusters. Finally, we will use enrichment analysis to identify different biological processes that underlay each clustered population.

Date/Time: Wednesday, May 28th, 10:30 AM Melbourne, Sydney, Brisbane / 8:30 AM Perth / Tuesday May 27th 5:30PM PDT USA
Registration link: https://www2.gotomeeting.com/register/403465030

*Please note that you must use your organizational e-mail address on the registration form. Those entering free e-mail accounts such as yahoo, gmail, etc. will be denied registration.

Nexus Copy Number was designed exclusively to provide an efficient, scalable, and intuitive means for research scientists to transform their raw genomic copy number data into biological insights. The software can integrate data from thousands of arrays along with their clinical annotations in a single project. Nexus Copy Number supports various array platforms and associated software including Agilent, Affymetrix, Illumina, GenePix, BlueFuse, ImaGene, Roche Nimblegen, Empire Genomics as well as custom data files.

For more information on Nexus Copy Number, please visit http://www.biodiscovery.com/index/nexus.

Seminars

Array-based Copy Number Analysis with Nexus Copy Number

In this presentation we will demonstrate the utility and efficiency of Nexus Copy Number by analyzing a number of different data sets. These will include a set of Breast Cancer samples (extracted from FFPE source and hybridized on Agilent 244K arrays) which will highlight Nexus’ ability to integrate phenotypic data as well as gene expression data by looking at the correlation of gene expression patterns from Her2 positive samples and overlay those with copy number gain regions obtained using CGH analysis. We will then show how genome-wide clustering can identify different groupings of samples based on copy number profiles and then show survival analysis on resulting clusters. Finally, we will use enrichment analysis to identify different biological processes that underlay each clustered population.

We will also show how Nexus can merge and integrate data from various array
platforms, such as Agilent aCGH, Affymetrix SNP, and Illumina SNP arrays, to identify
regions of minimal common overlap and correlate those with various phenotypic
factors. Time permitting we will also show samples of data from Nimblegen arrays for
identifying small aberrations in neurological disorders.

Date: Tuesday, May 20, 2008
Time: 2:00PM – 2:45PM, followed by a 10 min. Q & A
Location: Center for Human Genetics
Duke University
Genome Sciences Research Building 1, Room 4002
595 La Salle St., Durham, NC
Presenter: Soheil Shams, Ph.D., CSO, BioDiscovery Inc.

This is a free event. Click the link below to register for the seminar.

http://www.biodiscovery.com/index/biod-acgh-seminar-form/event.Duke

For more information on Nexus Copy Number, please visit http://www.biodiscovery.com/index/nexus.

Conferences

European Human Genetics Conference (ESHG 2008)
May 31 – June 2, Barcelona, Spain
Booth #428
http://www.eshg.org/eshg2008/index1.htm

Recent

AACR, April 13-16, 2008 San Diego, CA Booth #712

American Cytogenetics Conference, April 10-13, 2008 Monterey, CA

Breast and Brain Cancer Data Analysis with Nexus Copy Number, 3/11/08, 9:30AM - 10:30AM, Netherlands Cancer Institute

Copy Number Analysis using Nexus CGH Seminar, 2/6/08, 9:30-10:30AM, UHN

Copy Number Analysis using Nexus CGH Seminar, 1/23/08, 9:30-10:30AM, Harvard University, Boston, MA, Joseph B. Martin Conference Center

American Society for Human Genetics Annual Meeting (Booth 315), San Diego, CA, 10/23/07 - 10/27/07

Array Comparative Genomic Hybridization (aCGH) Analysis Seminar, 10/16, 1-2PM, Lund University, Wallenberg Centrum, BMC, Hus A , Sölvegatan 17

Array Comparative Genomic Hybridization (aCGH) Analysis Seminar, 10/17, 10-11AM, Karolinska University Hospital, CMM, Building L8:01, Seminar room

MC-GARD [Marie Curie Genome Architecture in Relation to Disease, Netherlands, 5/2/07 – 5/5/07

American Association for Cancer Research Annual Meeting 2007, Los Angeles, CA 4/14/07 - 4/18/07, Booth 1435

Microarray Image and aCGH Analysis plus Array Data Management and Analysis Seminar sponsored by Dr. Stan Nelson, UCLA Microarray Core Facility, Los Angeles, CA 3/8/07

City of Hope Microarray Seminar - Duarte, CA - 1/25/07