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Get an integrated analysis of copy number and sequence variation using data from The Cancer Genome Atlas (TCGA), and learn how CNV, allelic events, and seq. variations can aid in the discovery process in cancer studies.
This video will cover some basic principles of log ratios, how to identify regions of LOH, and some calling algorithms including HMM. Also, learn about the effect of mosaic loss or copy neutral LOH on the BAF profile.