New software feature Automated Genomic Scar Analysis for HRD with NxClinical Software

genomic scar karyogram tab
Enhanced transparency and clarity of chromosomal abnormalities to enable more accurate analysis of genomic scar instability Click to enlarge screen in new tab »

Bionano's NxClinicalTM  Software is the leading copy number variation (CNV) analysis software solution for cytogenetics and molecular laboratories. The latest software (v6.2) release adds three measures of genomic instability for homologous recombination repair deficiency (HRD) in solid tumors:

  • Loss of heterozygosity (LOH)
  • Telomeric Allelic Imbalance (TAI)
  • Large-Scale State Transitions (LST)

There are three processing steps involved in calculating these scores:

  1. Detecting CN and LOH events from arrays and next-generation sequencing (NGS)
  2. Merging and smoothing similar event types
  3. Selecting the resulting calls or breakpoints that comply with each scar’s specifications

NxClinical provides an automated, totaling of LOH, TAI, and LST allowing for rapid data analysis during case review. Results must then be verified by a qualified clinician.

To learn more about this NxClinical feature click below to register for a free demo.

Book a free demo »


webinar icon

Learn more about HRD and NxClinical automated analysis during this recent webinar

🎬Next-Generation Sequencing (NGS) Assessment of Homologous Recombination Deficiency (HRD): Expanding NGS Data to View Events Associated with Genomic Instability

Presented by:

Dr. Christopher Lum, M.D.
Medical Director, Molecular Diagnostics Laboratory at Diagnostic Laboratory Services, Inc.
Zan Halford, M.S. SMB(ASCP)CM,
Medical Technologist, Diagnostic Laboratory Services, Inc.

Watch the Webinar

Blog icon

Learn more about HRD and how NxClinical's automated scoring tool can help your lab.

📖Automating Genomic Scar Analysis For Homologous Recombination Deficiency (HRD): A Solution For Clinical Research Labs

Read the White Paper

Blog icon

Read more about the HRD Harmonization Project from Friends of Cancer Research

📰Homologous Recombination Deficiency: Concepts, Definitions, and Assays

Read Publication

Get the software trusted by renowned academic and commercial clinical labs to stay on top of demanding, time-sensitive workloads.

be creative_logo

Let’s talk.

Book a free personalized demo to assess fit and see NxClinical in action.

Seeing is believing! Let us know you’re interested and we’ll connect on an initial consultation to answer questions and dive a little deeper before demonstrating NXClinical—either with example data or your own.

Submit the request form and we’ll follow up to schedule a session at your convenience.