Nexus Copy Number
User-friendly and Powerful Statistical Tools
Arming researchers with advanced genomic data analysis and visualization tools. Easy-to-use software provides cutting-edge statistical tools to advance scientific discovery.
Features and Benefits
Identification of cooperating events, enrichment analysis, and clustering
Comparisons between genomic profiles to identify statistically significant differences
Analysis and visualization of multiple samples in parallel – no bioinformatics expertise required
Integration of mRNA, miRNA, sequence variants, methylation and copy number changes to identify genomic hotspots
Query for region/gene across multiple projects from GEO and TCGA via Nexus DB repository
Integrate phenotypic and genomic data to uncover significant correlations
Why Nexus Copy Number?
1. Copy Number from NGS & Microarray
Powered with the gold-standard CNV calling algorithm, Nexus Copy Number software derives copy number and BAF from a variety of NGS data (WES, WGS, targeted panel, and shallow sequencing) as well as Microarray data.
2. Support for all major instrument vendors for both NGS & Microarray
Nexus Copy Number is a multifaceted desktop software for rapid discovery of genomic alterations. This platform-agnostic software accepts data from various manufacturers and technologies including the latest platforms: Infinium GSA and CytoScan XON.
3. Powerful Research & Statistical Tools
The interactive visualization and powerful statistical tools allow detection of structural variations (e.g. copy number, homozygous regions), association with sequence variations (point mutations, InDels, inversions, etc.), and identification of statistically significant co-occurring up/down-regulated genes (from mRNA, miRNA, and RNASeq data).
See how easy it is to visualize and analyze your own data!
Customer Testimonials
We are longtime BioDiscovery customers starting with Nexus Copy Number software and now routinely using NxClinical software for interpretation of our clinical samples. NxClinical allows us to analyze CNVs and sequence variants together allowing rapid identification of compound events. Accurate detection of CNVs from NGS data using the MSR algorithm enhances the software capabilities in allowing us to derive all variants from a single assay. And the visualization within the software is second to none providing single base level views from sequencing reads, especially useful to rule out artifacts and confirm complex events. The cherry on top is the customer service. Clinical testing problems require fast solutions and the support team at BioDiscovery has always been extremely attentive to our needs.
- Dr. Benjamin Darbro, Assistant Professor of Pediatrics, Director of Shivanand R. Patil Cytogenetics and Molecular Laboratory, University of Iowa
Customer Testimonials
Nexus Copy Number is a powerful tool in our workflow, allowing direct visualization of data from numerous platforms, with a graphical interface that is as appealing as it is informative.
- Dr. Matthew Breen, Professor, Genomics, Oscar J. Fletcher Distinguished Professor, Comparative Oncology Genetics
Customer Testimonials
We have been using Nexus Copy Number and very happy with it. It allows direct visualization of data from different platforms with informative graphical interfaces. We integrated this powerful tool in our workflow.
- Dr. Yajuan Liu, Assistant Professor, Department of Pathology, University of Washington
Customer Testimonials
Nexus Copy Number provides a tremendously versatile means to integrate and interrogate data derived from multiple formats within a single interface.
- Rachael Thomas, Research Assistant Professor, Genomics, North Carolina State University
