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      NxClinical

      February 2022 - Towards diagnostic criteria for malignant deep penetrating melanocytic tumors using single nucleotide polymorphism array and next-generation sequencing

      Chiel F. Ebbelaar, Anne M. R. Schrader, Marijke van Dijk, Ruud W. J. Meijers, Wendy W. J. de Leng, Lourens T. Bloem, Anne M. L. Jansen & Willeke A. M. Blokx

      January 2022 - Intrinsic Cellular Susceptibility to Barrett’s Esophagus in Adults Born with Esophageal Atresia

      ten Kate, C.A.; de Klein, A.; de Graaf, B.M.; Doukas, M.; Koivusalo, A.; Pakarinen, M.P.; van der Helm, R.; Brands, T.; IJsselstijn, H.; van Bever, Y.; et al.

      [PubMed]

      January 2022 - Clinical Utility of Combined Optical Genome Mapping and 523-gene Next Generation Sequencing Panel For Comprehensive Evaluation of Myeloid Cancers

      Nikhil Shri Sahajpal, Ashis K Mondal, Sudha Ananth, Daniel Saul, Soheil Shams, Alex R Hastie, Natasha  M. Savage, Vamsi Kota, Alka Chaubey, Ravindra Kolhe

      May 2021- Novel compound heterozygous LRBA deletions in a 6-month old with neonatal diabetes

      May Sanyoura, Erika L. Lundgrin, Hari Subramanian, Min Yu, Priscilla Sodadasi, Siri Atma W. Greeley, Sarah MacLeish, Daniela del Gaudio

      [Abstract]

      April 2021 - A family harboring an MLKL loss of function variant implicates impaired necroptosis in diabetes

      Joanne M. Hildebrand, Bernice Lo, Sara Tomei, Valentina Mattei, Samuel N. Young, Cheree Fitzgibbon, James M. Murphy & Abeer Fadda

      April 2021 - Clinical Utility of Targeted Next-Generation Sequencing Assay to Detect Copy Number Variants Associated with Myelodysplastic Syndrome in Myeloid Malignancies

      Liqun Jiang, Aparna Pallavajjala, Jialing Huang, Lisa Haley, Laura Morsberger, Victoria Stinnett, Melanie Hardy, Rebecca Park, Candice Ament, Alexandra Finch, Alison Shane, Rebecca Parish, Azin Nozari, Patty Long, Emily Adams, Kirstin Smith, Vamsi Parimi, Sam Dougaparsad, Lori Long, Christopher Gocke, Ying Zou

      [Abstract]

      January 2021 - Dilated cardiomyopathy in a patient with autosomal dominant EEF1A2-related neurodevelopmental disorder.

      Maki Kaneko, Tena Rosser, Gordana Raca

      December 2020 - The Temple Grandin Genome: Comprehensive Analysis in a Scientist with High-Functioning Autism

      Rena J. Vanzo, Aparna Prasad, Lauren Staunch, Charles H. Hensel, Moises A. Serrano, E. Robert Wassman, Alexander Kaplun, Temple Grandin and Richard G. Boles

      [PubMed]

      June 2020 - Low-Pass Genome Sequencing: Validation and Diagnostic Utility from 409 Clinical Cases of Low-Pass Genome Sequencing for the Detection of Copy Number Variants to Replace Constitutional Microarray

      Alka Chaubey, Suresh Shenoy, Abhinav Mathur, Zeqiang Ma, C Alexander Valencia, Babi R Reddy Nallamilli, Edward Szekeres Jr, Leah Stansberry, Ruby Liu, Madhuri R Hegde

      [PubMed]

      May 2020 - Challenges in Establishing Pure Lung Cancer Organoids Limit Their Utility for Personalized Medicine

      Krijn K. Dijkstra, Kim Monkhorst, Luuk J. Schipper, Koen J. Hartemink, Egbert F. Smit, Sovann Kaing, Rosade Groot, Monika C. Wolkers, Hans Clevers, Edwin Cuppen, Emile E.Voest

      April 2020 - Infantile hypertrophic pyloric stenosis in patients with esophageal atresia

      Chantal A. ten Kate, Rutger W. W. Brouwer, Yolande van Bever, Vera K. Martens, Tom Brands, Nicole W. G. van Beelen, Alice S. Brooks, Daphne Huigh, Robert M. van der Helm, Bert H. F. M. M. Eussen, Wilfred F. J. van IJcken, Hanneke IJsselstijn, Dick Tibboel, Rene M. H. Wijnen, Annelies de Klein, Robert M. W. Hofstra, Erwin Brosens

      [PubMed]

      December 2019 - Validation Studies for Single Circulating Trophoblast Genetic Testing as a Form of Noninvasive Prenatal Diagnosis

      Liesbeth Vossaert, Qun Wang, Roseen Salman, Anne K. McCombs, Vipulkumar Patel, Chunjing Qu, Michael A. Mancini, Dean P. Edwards, Anna Malovannaya, Pengfei Liu, Chad A. Shaw, Brynn Levy, Ronald J. Wapner, Weimin Bi, Amy M. Breman, Ignatia B. Van den Veyver, Arthur L. Beaudet

      Nexus Copy Number

      October 2021 - Genome-wide association study identifies susceptibility loci for acute myeloid leukemia

      Wei-Yu Lin, Sarah E. Fordham, Eric Hungate, Nicola J. Sunter, Claire Elstob, Yaobo Xu, Catherine Park, Anne Quante, Konstantin Strauch, Christian Gieger, Andrew Skol, Thahira Rahman, Lara Sucheston-Campbell, Junke Wang, Theresa Hahn, Alyssa I. Clay-Gilmour, Gail L. Jones, Helen J. Marr, Graham H. Jackson, Tobias Menne, Mathew Collin, Adam Ivey, Robert K. Hills, Alan K. Burnett, Nigel H. Russell, Jude Fitzgibbon, Richard A. Larson, Michelle M. Le Beau, Wendy Stock, Olaf Heidenreich, Abrar Alharbi, David J. Allsup, Richard S. Houlston, Jean Norden, Anne M. Dickinson, Elisabeth Douglas, Clare Lendrem, Ann K. Daly, Louise Palm, Kim Piechocki, Sally Jeffries, Martin Bornhäuser, Christoph Röllig, Heidi Altmann, Leo Ruhnke, Desiree Kunadt, Lisa Wagenführ, Heather J. Cordell, Rebecca Darlay, Mette K. Andersen, Maria C. Fontana, Giovanni Martinelli, Giovani Marconi, Miguel A. Sanz, José Cervera, Inés Gómez-Seguí, Thomas Cluzeau, Chimène Moreilhon, Sophie Raynaud, Heinz Sill, Maria Teresa Voso, Francesco Lo-Coco, Hervé Dombret, Meyling Cheok, Claude Preudhomme, Rosemary E. Gale, David Linch, Julia Gaal-Wesinger, Andras Masszi, Daniel Nowak, Wolf-Karsten Hofmann, Amanda Gilkes, Kimmo Porkka, Jelena D. Milosevic Feenstra, Robert Kralovics, David Grimwade, Manja Meggendorfer, Torsten Haferlach, Szilvia Krizsán, Csaba Bödör, Friedrich Stölzel, Kenan Onel & James M. Allan

      August 2021 - Association of Combined Focal 22q11.22 Deletion and IKZF1 Alterations With Outcomes in Childhood Acute Lymphoblastic Leukemia

      David Spencer Mangum, MD; Julia A. Meyer, Ph.D.; Clinton C. Mason, Ph.D.; Soheil Shams, Ph.D.; Luke D. Maese, DO; Jamie D. Gardiner, Ph.D.; Jonathan M. Downie, MD, Ph.D.; Deqing Pei, MS; Cheng Cheng, Ph.D.; Adam Gleason, MS; Minjie Luo, Ph.D.; Ching-Hon Pui, MD; Richard Aplenc, MD, Ph.D.; Stephen P. Hunger, MD; Mignon Loh, MD; Mel Greaves, Ph.D.; Nikolaus Trede, MD, Ph.D.; Elizabeth Raetz, MD; J. Kimble Frazer, MD, Ph.D.; Charles G. Mullighan, MD; Michael E. Engel, MD, Ph.D.; Rodney R. Miles, MD, Ph.D.; Karen R. Rabin, MD, Ph.D.; Joshua D. Schiffman, MD

      August 2021 - Size matters: Large copy number losses in Hirschsprung disease patients reveal genes involved in enteric nervous system development

      Laura E. Kuil, Katherine C. MacKenzie, Clara S. Tang, Jonathan D. Windster, Thuy Linh Le, Anwarul Karim, Bianca M. de Graaf, Robert van der Helm, Yolande van Bever, Cornelius E. J. Sloots, Conny Meeussen, Dick Tibboel, Annelies de Klein, René M. H. Wijnen, Jeanne Amiel, Stanislas Lyonnet, Maria-Mercè Garcia-Barcelo, Paul K. H. Tam, Maria M. Alves, Alice S. Brooks, Robert M. W. Hofstra, Erwin Brosens

      May 2021 - Single nucleotide polymorphism array-based signature of low hypodiploidy in acute lymphoblastic leukemia

      Thomas Creasey, Amir Enshaei, Karin Nebral, Claire Schwab, Kathryn Watts, Gavin Cuthbert, Ajay Vora,  John Moppett, Christine J. Harrison, Adele K. Fielding, Oskar A. Haas, Anthony V. Moorman

      May 2021 - Copy number and transcriptome alterations associated with metastatic lesion response to treatment in colorectal cancer

      Karen Gambaro, Maud Marques, Suzan McNamara, Mathilde Couetoux du Tertre, Zuanel Diaz, Cyrla Hoffert, Archana Srivastava, Steven Hébert, Benoit Samson, Bernard Lespérance, Yoo‐Joung Ko, Richard Dalfen, Eve St‐Hilaire, Lucas Sideris, Felix Couture, Ronald Burkes, Mohammed Harb, Errol Camlioglu, Adrian Gologan, Vincent Pelsser, André Constantin, Celia M.T. Greenwood, Sabine Tejpar, Petr Kavan, Claudia L. Kleinman, Gerald Batist

      January 2021 - Genome-wide association study identifies risk loci for progressive chronic lymphocytic leukemia

      Wei-Yu Lin, Sarah E. Fordham, Nicola Sunter, Claire Elstob, Thahira Rahman, Elaine Willmore, Colin Shepherd, Gordon Strathdee, Tryfonia Mainou-Fowler, Rachel Piddock, Hannah Mearns, Timothy Barrow, Richard S. Houlston, Helen Marr, Jonathan Wallis, Geoffrey Summerfield, Scott Marshall, Andrew Pettitt, Christopher Pepper, Christopher Fegan, Francesco Forconi, Martin J. S. Dyer, Sandrine Jayne, April Sellors, Anna Schuh, Pauline Robbe, David Oscier, James Bailey, Syed Rais, Alison Bentley, Lynn Cawkwell, Paul Evans, Peter Hillmen, Guy Pratt, David J. Allsup & James M. Allan

      April 2020 - Rapid Low-Cost Microarray-Based Genotyping for Genetic Screening in Primary Immunodeficiency

      Narissara Suratannon, Rogier T. A. van Wijck, Linda Broer, Laixi Xue, Joyce B. J. van Meurs, Barbara H. Barendregt, Mirjam van der Burg, Willem A. Dik, Pantipa Chatchatee, Anton W. Langerak, Sigrid M. A. Swagemakers, Jacqueline A. C. Goos, Irene M. J. Mathijssen,  Virgil A. S. H. Dalm, Kanya Suphapeetiporn, Kim C. Heezen, Jose Drabwell, André G. Uitterlinden, Peter J. van der Spek, P. Martin van Hagen and the South East Asia Primary Immunodeficiencies (SEAPID) Consortium.

      October 2018 - Dynamics of genome alterations in Crohn's disease associated colorectal carcinogenesis

      Daniela Hirsch, Darawalee Wangsa, Yuelin J Zhu, Yue Hu, Daniel C Edelman, Paul S. Meltzer, Kerstin Heselmeyer-Haddad, Claudia Ott, Peter Kienle, Christian Galata, Karoline Horisberger, Thomas Ried and Timo Gaiser. Clinical Cancer Research; Biology of Human Tumors; AACR Publications. July 2018.

      July 2018 - A new molecular assay and genomic complexity predict outcome in conventional and leukemic non-nodal mantle cell lymphoma

      Guillem Clot, Pedro Jares, Eva Giné, Alba Navarro, Cristina Royo, Magda Pinyol, David Martín-Garcia, Santiago Demajo, Blanca Espinet, Antonio Salar, Ana Ferrer, Ana Muntañola, Marta Aymerich, Hilka Rauert-Wunderlich, Elaine S. Jaffe, Joseph M. Connors, Randy D. Gascoyne, Jan Delabie, Armando López-Guillermo, German Ott, George W. Wright, Louis M. Staudt, Andreas Rosenwald, David W. Scott, Lisa M. Rimsza, Sílvia Beà and Elías Campo. Blood 2018 :blood-2018-03-838136. May 10, 2018.

      Expanded Genomic Profiling of Circulating Tumor Cells in Metastatic Breast Cancer Patients to Assess Biomarker Status and Biology Over Time (CALGB 40502 and CALGB 40503, Alliance)

       

      Mark Jesus M. Magbanua, Hope S. Rugo, Denise M. Wolf, Louai Hauranieh, Ritu Roy, Praveen Pendyala, Eduardo V. Sosa, Janet H. Scott, Jin Sun Lee, Brandelyn Pitcher, Terry Hyslop, William T. Barry, Steven J. Isakoff, Maura Dickler, Laura van't Veer and John W. Park.Clinical Cancer Research; Biology of Human Tumors; AACR Publications. March 2018.

      A MUTYH germline mutation is associated with small intestinal neuroendocrine tumors.

       

      Jan P. Dumanski, Chiara Rasi, Peyman Björklund, Hanna Davies, Abir Salwa Ali, Malin Grönberg, Staffan Welin, Halfdan Sorbye, Henning Grønbæk, Janet Cunningham, Lars A. Forsberg, Lars Lind, Erik Ingelsson, Peter Stalberg, Per Hellman and Eva Tiensuu Janson. Endocr Relat Cancer. 2017 June 20. [Epub ahead of print]

      Genomic landscape and evolution of metastatic chromophobe renal cell carcinoma.

       

      Casuscelli J, Weinhold N, Gundem G, Wang L, Zabor EC, Drill E, Wang PI, Nanjangud GJ, Redzematovic A, Nargund AM, Manley BJ, Arcila ME, Donin NM, Cheville JC, Thompson RH, Pantuck AJ, Russo P, Cheng EH, Lee W, Tickoo SK, Ostrovnaya I, Creighton CJ, Papaemmanuil E, Seshan VE, Hakimi AA, Hsieh JJ. JCI Insight. 2017 Jun 15;2(12). [Epub ahead of print]

      Microarray analysis to identifiy novel copy number alterations in acute myeloid leukemia.

       

      Maria Chiara Fontana, Giovanni Marconi, Cristina Papayannidis, Eugenio Fonzi, Emanuela Ottaviani, Eugenia Franchini, Anna Ferrari, Giorgia Simonetti, Antonella Padella, Samantha Bruno, Nicoletta Testoni, Carmen Baldazzi, Andrea Ghelli Luserna di Rorà, Valentina Robustell†, Maria Chiara Abbenante, Stefania Paolini, Jacopo Nanni, Luca Bertamini, Giovanni Martinelli. Journal of Clinical Oncology. 2017 May;35(15_suppl):11622-11622.

      Precision Medicine Analysis Of 203 Pediatric Brain Tumors Reveals Clinically Relevant Genomic Alterations

       

      Pratiti Bandopadhayay Shakti Ramkissoon Jaeho Hwang Lori Ramkissoon Noah Greenwald Steven Schumacher Ryan O’Rourke Nathan Pinches Patricia Ho Hayley Malkin Claire Sinai Mariella Filbin Ashley Plant Wenya Bi Michael Chang Edward Yang Karen Wright Peter Manley Matthew Ducar Sanda Alexandrescu Hart Lidov Ivana Delalle Liliana Goumnerova Alanna Church Katherine Janeway Marian Harris Laura MacConaill Rebecca Folkerth Neal Lindeman Charles Stiles Mark Kieran Azra Ligon Sandro Santagata Adrian Dubuc Susan Chi Rameen Beroukhim Keith Ligon. Neuro Oncol (2017) 19 (suppl_4): iv20.

      Genomic imbalances in syndromic congenital heart disease.

       

      Coelho Molck M, Simioni M, Paiva Vieira T, Sgardioli IC, Paoli Monteiro F, Souza J, Fett-Conte AC, Félix TM, Lopes Monlléo I, Gil-da-Silva-Lopes VL. J Pediatr (Rio J). 2017 Mar 21. pii: S0021-7557(17)30218-8. doi: 10.1016/j.jped.2016.11.007. [Epub ahead of print]

      Application of high-resolution genomic profiling in the differential diagnosis of liposarcoma.

       

      Koczkowska M, Lipska-Ziętkiewicz BS, Iliszko M, Ryś J, Miettinen M, Lasota J, Biernat W, Harazin-Lechowska A, Kruczak A, Limon J. Mol Cytogenet. 2017 Mar 16;10:7.

      Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice.

       

      Halim D, Wilson MP, Oliver D, Brosens E, Verheij JB, Han Y, Nanda V, Lyu Q, Doukas M, Stoop H, Brouwer RW, van IJcken WF, Slivano OJ, Burns AJ, Christie CK, de Mesy Bentley KL, Brooks AS, Tibboel D, Xu S, Jin ZG, Djuwantono T, Yan W, Alves MM, Hofstra RM, Miano JM. Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):E2739-E2747. doi: 10.1073/pnas.1620507114. Epub 2017 Mar 14.

      Whole exome sequencing coupled with unbiased functional analysis reveals new Hirschsprung disease genes.

       

      Gui H, Schriemer D, Cheng WW, Chauhan RK, Antiňolo G, Berrios C, Bleda M, Brooks AS, Brouwer RW, Burns AJ, Cherny SS, Dopazo J, Eggen BJ, Griseri P, Jalloh B, Le TL, Lui VC, Luzón-Toro B, Matera I, Ngan ES, Pelet A, Ruiz-Ferrer M, Sham PC, Shepherd IT, So MT, Sribudiani Y, Tang CS, van den Hout MC, van der Linde HC, van Ham TJ, van IJcken WF, Verheij JB, Amiel J, Borrego S, Ceccherini I, Chakravarti A, Lyonnet S, Tam PK, Garcia-Barceló MM, Hofstra RM. Genome Biol. 2017 Mar 8;18(1):48. doi: 10.1186/s13059-017-1174-6.

      TFEB Amplification Renal Cell Carcinoma Detected by Chromosome Genomic Array: A Case Report for Diagnosis of a Novel Entity.

       

      Qu X, Chen Y, Thompson JA, Lin D, et al. J Clin Mol Pathol. 2017 Feb 18; 1: 07.

      PIK3CA mutations are common in lobular carcinoma in situ, but are not a biomarker of progression

       

      Shah V, Nowinski S, Levi D, Shinomiya I, Kebaier Ep Chaabouni N, Gillett C, Grigoriadis A, Graham TA, Roylance R, Simpson MA, Pinder SE, Sawyer EJ. Breast Cancer Res. 2017 Jan 17;19(1):7.

      Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories

       

      Taylor RA, Fraser M, Livingstone J, Espiritu SM, Thorne H, Huang V, Lo W, Shiah YJ, Yamaguchi TN, Sliwinski A, Horsburgh S, Meng A, Heisler LE, Yu N, Yousif F, Papargiris M, Lawrence MG, Timms L, Murphy DG, Frydenberg M, Hopkins JF, Bolton D, Clouston D, McPherson JD, van der Kwast T, Boutros PC, Risbridger GP, Bristow RG. Nat Commun. 2017 Jan 9;8:13671.

      Genomic hallmarks of localized, non-indolent prostate cancer

       

      Michael Fraser, Veronica Y. Sabelnykova, Takafumi N. Yamaguchi, Lawrence E. Heisler, Julie Livingstone, Vincent Huang, Yu-Jia Shiah, Fouad Yousif, Xihui Lin, Andre P. Masella, Natalie S. Fox, Michael Xie, Stephenie D. Prokopec, Alejandro Berlin, Emilie Lalonde, Musaddeque Ahmed, Dominique Trudel, Xuemei Luo, Timothy A. Beck, Alice Meng, Junyan Zhang, Alister D’Costa, Robert E. Denroche, Haiying Kong, Shadrielle Melijah G. Espiritu, Melvin L. K. Chua, Ada Wong, Taryne Chong, Michelle Sam, Jeremy Johns, Lee Timms, Nicholas B. Buchner, Michèle Orain, Valérie Picard, Helène Hovington, Alexander Murison, Ken Kron, Nicholas J. Harding, Christine P’ng, Kathleen E. Houlahan, Kenneth C. Chu, Bryan Lo, Francis Nguyen, Constance H. Li, Ren X. Sun, Richard de Borja, Christopher I. Cooper, Julia F. Hopkins, Shaylan K. Govind, Clement Fung, Daryl Waggott, Jeffrey Green, Syed Haider, Michelle A. Chan-Seng-Yue, Esther Jung, Zhiyuan Wang, Alain Bergeron, Alan Dal Pra, Louis Lacombe, Colin C. Collins, Cenk Sahinalp, Mathieu Lupien, Neil E. Fleshner, Housheng H. He, Yves Fradet, Bernard Tetu, Theodorus van der Kwast, John D. McPherson, Robert G. Bristow & Paul C. Boutros. Nature. 2017 Jan 9. [Epub ahead of print]

      Complex Mosaic Ring Chromosome 11 Associated with Hemizygous Loss of 8.6 Mb of 11q24.2qter in Atypical Jacobsen Syndrome

       

      Galvão Gomes A. Paiva Grangeiro C.H. Silva L.R. Oliveira-Gennaro F.G. Pereira C.S. Joaquim T.M. Panepucci R.A. Squire J.A. Martelli L. Mol Syndromol 2017;8:45-49 (DOI:10.1159/000452681)

      Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study.

       

      Shi J, Hua X, Zhu B, Ravichandran S, Wang M, Nguyen C, Brodie SA, Palleschi A, Alloisio M, Pariscenti G, Jones K, Zhou W, Bouk AJ, Boland J, Hicks B, Risch A, Bennett H, Luke BT, Song L, Duan J, Liu P, Kohno T, Chen Q, Meerzaman D, Marconett C, Laird-Offringa I, Mills I, Caporaso NE, Gail MH, Pesatori AC, Consonni D, Bertazzi PA, Chanock SJ, Landi MT. PLoS Med. 2016 Dec 6;13(12):e1002162.

      Single-neuron and genetic correlates of autistic behavior in macaque

       

      Yoshida K, Go Y, Kushima I, Toyoda A, Fujiyama A, Imai H, Saito N, Iriki A, Ozaki N, Isoda M. Sci Adv. 2016 Sep 21;2(9):e1600558.

      Early G1 cyclin-dependent kinases as prognostic markers and potential therapeutic targets in esophageal adenocarcinoma

       

      Amin Ismail*, Santhoshi Bandla, Marie Reveiller, Liana Toia, Zhongren Zhou, William E Gooding, Irina Kalatskaya, Lincoln Stein, Mary D’Souza, Virginia R Litle, Jeffrey H Peters, Arjun Pennathur, James D. Luketich, and Tony E Godfrey. Clin Cancer Res. 2011 May 18. [Epub ahead of print]

      Molecular Karyotypes of Hodgkin and Reed-Sternberg Cells at Disease Onset Reveal Distinct Copy Number Alterations in Chemosensitive versus Refractory Hodgkin Lymphoma

       

      Slovak ML, Bedell V, Hsu YH, Estrine DB, Nowak NJ, Delioukina ML, Weiss LM, Smith DD, Forman SJ. Clin Cancer Res. 2011 May 15;17(10):3443-54. Epub 2011 Mar 8.

      Array-based genomic screening at diagnosis and follow-up in chronic lymphocytic leukemia

       

      Gunnarsson R, Mansouri L, Isaksson A, Goransson H, Cahill N, Jansson M, Rasmussen M, Lundin J, Norin S, Buhl AM, Ekstrom Smedby K, Hjalgrim H, Karlsson K, Jurlander J, Geisler C, Juliusson G, Rosenquist R. Haematologica. 2011 May 5. [Epub ahead of print]

      [Abstract]

      Recognition of potential predictive markers for diagnosis in Korean serous ovarian cancer patients at stage IIIc using array comparative genomic hybridization with high resolution

       

      Jee Young Kwon, Young Rok Seo and Woong Shick Ahn. Molecular & Cellular Toxicology. 2011 Mar; 7(1):77-86.

      A new 17p13.3 microduplication including the PAFAH1B1 and YWHAE genes resulting from an unbalanced X;17 translocation

       

      Hyon C, Marlin S, Chantot-Bastaraud S, Mabboux P, Beaujard MP, Al Ageeli E, Vazquez MP, Picard A, Siffroi JP, Portnoï MF. Eur J Med Genet. 2010 Dec 31. [Epub ahead of print]

      Archival Fine-Needle Aspiration Cytopathology (FNAC) Samples Untapped Resource for Clinical Molecular Profiling

       

      J. Keith Killian, Robert L. Walker, Miia Suuriniemi, Laura Jones, Stephanie Scurci, Parvati Singh, Robert Cornelison, Shannon Harmon, Nichole Boisvert, Jack Zhu, Yonghong Wang, Sven Bilke, Sean Davis, Giuseppe Giaccone , William I. Smith, Jr and Paul S. Meltzer. J Mol Diagn. Nov 2010; 12: 739-745

      Gene copy number variation in male breast cancer by aCGH

       

      Stefania Tommasi, Anita Mangia, Giuseppina Iannelli, Patrizia Chiarappa, Elena Rossi, Laura Ottini, Marcella Mottolese, Wainer Zoli, Orsetta Zuffardi, Angelo Paradiso. 2010 Nov. Analytical Cellular Pathology / Cellular Oncology.

      Distinctive Phenotypic Abnormalities Associated with Submicroscopic 21q22 Deletion Including DYRK1A

       

      R. Oegemaa, A. de Kleina, A.J. Verkerkb, R. Schota, B. Dumeeb, H. Doubena, B. Eussena, L. Dubbela, P.J. Poddighea, I. van der Laara, W.B. Dobynsc, P.J. van der Spekb, M.H. Lequind, I.F.M. de Cooe, M.-C.Y. de Wite, M.W. Wesselsa, G.M.S. Mancinia. Mol Syndromol 2010 Sept; 1:113-120.

      No Haploinsufficiency but Loss of Heterozygosity for EXT in Multiple Osteochondromas

       

      Reijnders CM, Waaijer CJ, Hamilton A, Buddingh EP, Dijkstra SP, Ham J, Bakker E, Szuhai K, Karperien M, Hogendoorn PC, Stringer SE, Bovée JV. Am J Pathol. 2010 Oct;177(4):1946-57. Epub 2010 Sep 2.

      [Abstract]

      Oligonucleotide-based array CGH analysis of diffuse large B-cell lymphomas identifies gain of 7q22 as the most common genomic alteration

       

      Edward A. Medina, Aswani R Bolla, Rajya L Bandi and Ryan S Robetorye. FASEB J. 2010 24:954.11.

      A novel mutation of GATA4 in a familial atrial septal defect

       

      Chen Y, Mao J, Sun Y, Zhang Q, Cheng HB, Yan WH, Choy KW, Li H. Clin Chim Acta. 2010 Jul 24. [Epub ahead of print]

      NF1 Is a Tumor Suppressor in Neuroblastoma that Determines Retinoic Acid Response and Disease Outcome

       

      Michael Hölzel, Sidong Huang, Jan Koster, Ingrid Øra, Arjan Lakeman, Huib Caron, Wouter Nijkamp, Jing Xie, Tom Callens, Shahab Asgharzadeh, Robert C. Seeger, Ludwine Messiaen, Rogier Versteeg, René Bernards. Cell – 23 July 2010

      Patterns and incidence of chromosomal instability and their prognostic relevance in breast cancer subtypes

       

      Smid M, Hoes M, Sieuwerts AM, Sleijfer S, Zhang Y, Wang Y, Foekens JA, Martens JW. Breast Cancer Res Treat. 2010 Jul 15. [Epub ahead of print]

      Application of Nexus Copy Number Software for CNV Detection and Analysis.

       

      Bert Eussen and Annelies de Klein. European Cytogeneticists Association Newsletter. July 2010.

      Clinical Implications of Gene Dosage and Gene Expression Patterns in Diploid Breast Carcinoma.

       

      Parris TZ, Danielsson A, Nemes S, Kovács A, Delle U, Fallenius G, Möllerström E, Karlsson P, Helou K. Clin Cancer Res. 2010 Jun 15.

      HDMX regulates p53 activity and confers chemoresistance to 3-Bis (2-chloroethyl)-1-nitrosoureaG

       

      Jin G, Cook S, Cui B, Chen WC, Keir ST, Killela P, Di C, Payne CA, Gregory SG, McLendon R, Bigner DD, Yan H. Neuro Oncol. 2010 May 14. [Epub ahead of print]

      [Abstract]

      Tourette disorder spectrum maps to chromosome 14q31. 1 in an Italian kindred

       

      Breedveld GJ, Fabbrini G, Oostra BA, Berardelli A, Bonifati V. Neurogenetics. 2010 May 2. [Epub ahead of print]

      Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis.

       

      Baranzini SE, Mudge J, van Velkinburgh JC, Khankhanian P, Khrebtukova I, Miller NA, Zhang L, Farmer AD, Bell CJ, Kim RW, May GD, Woodward JE, Caillier SJ, McElroy JP, Gomez R, Pando MJ, Clendenen LE, Ganusova EE, Schilkey FD, Ramaraj T, Khan OA, Huntley JJ, Luo S, Kwok PY, Wu TD, Schroth GP, Oksenberg JR, Hauser SL, Kingsmore SF. Nature. 2010 Apr 29;464(7293):1351-6.

      High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with “stereotyped” IGHV3-21 and IGHV4-34 B cell receptors

       

      Marincevic M, Cahill N, Gunnarsson R, Isaksson A, Mansouri M, Göransson H, Rasmusson M, Jansson M, Ryan F, Karlsson K, Adami HO, Davi F, Jurlander J, Juliusson G, Stamatopoulus K, Rosenquist R. Haematologica. 2010 Apr 26. [Epub ahead of print]

      Genetics of uveal melanoma

       

      Hanneke W Mensink, Dion Paridaens, Annelies de Klein Expert Review of Ophthalmology, December 2009, Vol. 4, No. 6, Pages 607-616.

      Copy number variations are a rare cause of non-CMT1A Charcot-Marie-Tooth disease.

       

      Huang J, Wu X, Montenegro G, Price J, Wang G, Vance JM, Shy ME, Züchner S. J Neurol. 2009 Dec 1.

      Genomic Landscape of Meningiomas.

       

      Lee Y, Liu J, Patel S, Cloughesy T, Lai A, Farooqi H, Seligson D, Dong J, Liau L, Becker D, Mischel P, Shams S, Nelson S.Brain Pathol. 2009 Nov 20.

      High resolution discovery and confirmation of copy number variants in 90 Yoruba Nigerians

       

      Hajime Matsuzaki , Pei-Hua Wang , Jing Hu , Rich Rava and Glenn K Fu, Genome Biology 2009, 9 Nov., 10:R125

      Microarray based analysis of 3p25-p26 deletions (3p- syndrome).

       

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      Anderson TJ, Patel J, Ferdig MT. Trends Parasitol. 2009 Jul;25(7):336-43. Epub 2009 Jun 24.

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      Detection of copy number alterations in metastatic melanoma by a DNA fluorescence in situ hybridization probe panel and array comparative genomic hybridization: a southwest oncology group study (S9431)

       

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      Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia

       

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      A de-novo 7.6 Mb tandem duplication of 14q32.2-qter associated with primordial short stature with neurosecretory growth hormone dysfunction, distinct facial anomalies and mild developmental delay

       

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      3.8 MB Deletion of Chromosome 5q in a Newborn Tracheal Agenesis Patient

       

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      Overexpression of Transcobalamin 1 is an Independent Negative Prognosticator in Rectal Cancers Receiving Concurrent Chemoradiotherapy.

       

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      Downregulation of RNF128 Predicts Progression and Poor Prognosis in Patients with Urothelial Carcinoma of the Upper Tract and Urinary Bladder

       

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      Chai CY, Zhang Y, Song J, Lin SC, Sun S, Chang IW. Am J Transl Res. 2016 Oct 15;8(10):4455-4463.

       

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      ASS1 as a Novel Tumor Suppressor Gene in Myxofibrosarcoma: Aberrant loss via epigenetic DNA methylation confers aggressive phenotypes, negative prognostic impact, and therapeutic relevance.

       

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      DNA Damage-Mediated c-Myc Degradation Requires 14-3-3 Sigma

       

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      Gene expression in thyroid autonomous adenomas provides insight into their physiopathology.

       

      Sandrine Wattel, Hortensia Mircescu, David Venet, Agnes Burniat, Brigitte Franc, Sandra Frank, Guy Andry, Jacqueline Van Sande, Pierre Rocmans, Jacques E Dumont, Vincent … Gene expression in thyroid autonomous adenomas provides insight into their physiopathology. Oncogene , (18 Jul 2005)

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      The transcriptome of HCV replicon expressing cell lines in the presence of alpha interferon

       

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      Altered gene expression in phenotypically normal renal cells from carriers of tumor suppressor gene mutations

       

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      The Global Error Assessment Model for the Selection of Differentially Expressed Genes in Microarray Data

       

      Mansourian, R., Mutch, D., Antille, N., Aubert, J., Fogel, P., Goff, J., Moulin, J., Petrov, A., Rytz, A., Voegel, J., Roberts, M., The Global Error Assessment Model for the Selection of Differentially Expressed Genes in Microarray Data, scheduled to appear in Bioinformatics in September 2004.

      Microarray analysis identified differentially expressed genes in keratocytes from keratoconus patients

       

      Ha NT, Nakayasu K, Murakami A, Ishidoh K, Kanai A. Microarray analysis identified differentially expressed genes in keratocytes from keratoconus patients. Curr Eye Res. 2004 Jun;28(6):373-9. PMID: 15512944 [PubMed – indexed for MEDLINE]

      Plakoglobin is a new target gene of histone deacetylase in human fibrosarcoma HT1080 cells

       

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      DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray.

       

      Siew Loon Ooi, Daniel D Shoemaker, Jef D Boeke. DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray. Nature Genetics 35, 277-286 (01 Nov 2003)

      Disruption of the c-JUN-JNK Complex by a Cell-permeable Peptide Containing the c-JUN Domain Induces Apoptosis and Affects a Distinct Set of Interleukin-1-induced Inflammatory Genes.

       

      Holzberg, David , C. Graham Knight, Oliver Dittrich-Breiholz, Heike Schneider, Anneke Dörrie, Elke Hoffmann, Klaus Resch, and Michael Kracht. Disruption of the c-JUN-JNK Complex by a Cell-permeable Peptide Containing the c-JUN Domain Induces Apoptosis and Affects a Distinct Set of Interleukin-1-induced Inflammatory Genes. J. Biol. Chem., Oct 2003; 278: 40213 – 40223.

      Structure-activity relationship of synthetic toll-like receptor 4 agonists.

       

      Stöver, Axel G. , Jean Da Silva Correia, Jay T. Evans, Christopher W. Cluff, Mark W. Elliott, Eric W. Jeffery, David A. Johnson, Michael J. Lacy, Jory R. Baldridge, Peter Probst, Richard J. Ulevitch, David H. Persing, and Robert M. Hershberg. Structure-activity relationship of synthetic toll-like receptor 4 agonists. J. Biol. Chem., Oct 2003; 10.1074/jbc.M310760200

      Screening for ovarian cancer-associated genes with cDNA microarrays

       

      Zhang XY, Li XP, Lai J, Feng J. Screening for ovarian cancer-associated genes with cDNA microarrays. Ai Zheng. 2003 Sep;22(9):943-7. Chinese. PMID: 12969526 [PubMed – indexed for MEDLINE]

      Adult midgut expressed sequence tags from the tsetse fly Glossina morsitans morsitans and expression analysis of putative immune response genes

       

      Lehane MJ, Aksoy S, Gibson W, Kerhornou A, Berriman M, Hamilton J, Soares MB, Bonaldo MF, Lehane S, Hall N . Adult midgut expressed sequence tags from the tsetse fly Glossina morsitans morsitans and expression analysis of putative immune response genes. Genome Biology 2003, 4(10):R63 (11 September 2003) http://genomebiology.com/2003/4/10/R63

      Computational Methods for Selection of Differentially Regulated Genes in Cell Immortalization

       

      Draghici, S., Kulaeva, O., Hoff, B., Petrov, A., Shams, S., Tainsky, M. A. , Computational Methods for Selection of Differentially Regulated Genes in Cell Immortalization, Bioinformatics, September 2003

      Noise Sampling Method: an ANOVA Approach Allowing Robust Selection of Differentially Regulated Genes Measured by DNA Microarrays, Bioinformatics

       

      Draghici S, Kulaeva O, Hoff B, Petrov A, Shams S, Tainsky MA (2003) Noise Sampling Method: an ANOVA Approach Allowing Robust Selection of Differentially Regulated Genes Measured by DNA Microarrays, Bioinformatics, 2003 Jul 22;19(11):1348-59

      Epigenetic silencing of multiple interferon pathway genes after cellular immortalization

       

      Olga I Kulaeva, Sorin Draghici, Lin Tang, Janice M Kraniak, Susan J Land, Michael A Tainsky. . Epigenetic silencing of multiple interferon pathway genes after cellular immortalization. Oncogene 22, 4118-4127 (26 Jun 2003)

      Genomic Expression Discovery Predicts Pathways and Opposing Functions behind Phenotypes

       

      Fathallah-Shaykh, Hassan M., He, Bin, Zhao, Li-Juan, Engelhard, Herbert H., Cerullo, Leonard, Lichtor, Terry, Byrne, Richard, Munoz, Lorenzo, Von Roenn, Kelvin, Rosseau, Gail L., Glick, Roberta, Sherman, Chen, and Farooq, Khan . Genomic Expression Discovery Predicts Pathways and Opposing Functions behind Phenotypes. J. Biol. Chem., Jun 2003; 278: 23830 – 23833.

      Molecular network and functional implications of macromolecular tRNA synthetase complex

       

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      Analysis of Gene Expression Profile of Pancreatic Carcinoma using cDNA Microarray.

       

      Tan ZJ, Hu XG, Cao GS, Tang Y. Analysis of Gene Expression Profile of Pancreatic Carcinoma using cDNA Microarray. World J Gastroenterol. 2003 Apr;9(4):818-23.

      Transcriptome analysis of Sinorhizobium meliloti during symbiosis.

       

      Frederic Ampe, Ernö Kiss, Frédérique Sabourdy, Jacques Batut. Transcriptome analysis of Sinorhizobium meliloti during symbiosis. Genome Biology 2003 4:R15 http://genomebiology.com/2003/4/2/r15

      Bikunin Target Genes in Ovarian Cancer Cells Identified by Microarray Analysis

       

      Suzuki, Mika , Hiroshi Kobayashi, Yoshiko Tanaka, Yasuyuki Hirashima, Naohiro Kanayama, Yuji Takei, Yasushi Saga, Mitsuaki Suzuki, Hiroshi Itoh, and Toshihiko Terao. Bikunin Target Genes in Ovarian Cancer Cells Identified by Microarray Analysis. J. Biol. Chem., Apr 2003; 278: 14640 – 14646.

      Difference of gene expression profiles between esophageal carcinoma and its pericancerous epithelium by gene chip

       

      Xu SH, Qian LJ, Mou HZ, Zhu CH, Zhou XM, Liu XL, Chen Y, Bao WY. Difference of gene expression profiles between esophageal carcinoma and its pericancerous epithelium by gene chip. World J Gastroenterol. 2003 Mar; 9(3): 417-22. PMID: 12632488 [PubMed – indexed for MEDLINE]

      Gene-engineered Rigidification of Membrane Lipids Enhances the Cold Inducibility of Gene Expression in Synechocystis

       

      Inaba, Masami , Iwane Suzuki, Balázs Szalontai, Yu Kanesaki, Dmitry A. Los, Hidenori Hayashi, and Norio Murata. Gene-engineered Rigidification of Membrane Lipids Enhances the Cold Inducibility of Gene Expression in Synechocystis. J. Biol. Chem., Mar 2003; 278: 12191 – 12198.

      Preadipocyte Conversion to Macrophage. EVIDENCE OF PLASTICITY.

       

      Charrière, G., Cousin, B., Arnaud, E., André, M., Bacou, F., Pénicaud, L., and Casteilla, L. . Preadipocyte Conversion to Macrophage. EVIDENCE OF PLASTICITY. J. Biol. Chem., Mar 2003; 278: 9850 – 9855.

      Up-regulated Smad5 Mediates Apoptosis of Gastric Epithelial Cells Induced by Helicobacter

       

      Nagasako, Tomokazu , Toshiro Sugiyama, Takuji Mizushima, Yosuke Miura, Mototsugu Kato, and Masahiro Asaka. Up-regulated Smad5 Mediates Apoptosis of Gastric Epithelial Cells Induced by Helicobacter pylori Infection. J. Biol. Chem., Feb 2003; 278: 4821 – 4825.

      Significance Testing Among Groups using GeneSight, in Data Analysis Tools for Microarrays,

       

      Hoff B, Significance Testing Among Groups using GeneSight, in Data Analysis Tools for Microarrays, S. Draghici ed., Chapman and Hall/CRC Press, 2003.

      A Comprehensive Microarray Data Management Approach in Microarrays Methods and Applications: Nuts & Bolts

       

      Kiyoko AF, Petrov, A., A Comprehensive Microarray Data Management Approach in Microarrays Methods and Applications: Nuts & Bolts, G. Hardimann (ed.), DNA Press (2003)

      Image Analysis Issues and Solutions for High-Density Arrays in Protein Microarray Technology

       

      Petrov, A., Shams, S., Image Analysis Issues and Solutions for High-Density Arrays in Protein Microarray Technology, Dev Kambhampati (ed.), Wiley Publishers (2003)

      Gene Expression-Based Tumor Classification with GeneSight from BioDiscovery, Inc.

       

      Hoff, B., Shams, S., Kuklin, A. Gene Expression-Based Tumor Classification with GeneSight from BioDiscovery, Inc., Dispatches from the Forefront of Array BioInformatics Vol. 1, No.,

      An Emerging Technology for the Characterization of Antibodies Biotechniques

       

      Schwenk,Jochen M., Stroll, Dieter, Templin, Markus F., And Joos, Thomas O. Cell Microarrays : An Emerging Technology for the Characterization of Antibodies Biotechniques 33:S54-61 December 2002.

      Pathway Confers Basement Membrane Dependence upon Endoderm Differentiation of Embryonic Carcinoma Cells.

       

      Smedberg, Jennifer L., Smith, Elizabeth R., Capo-chichi, Callinice D., Frolov, Andrey, Yang, Dong-Hua, Godwin, Andrew K., and Xu, Xiang-Xi Ras/MAPK Pathway Confers Basement Membrane Dependence upon Endoderm Differentiation of Embryonic Carcinoma Cells. J. Biol. Chem., Oct 2002; 277: 40911 – 40918.

      Global Expression Profiling of Acetate-grown Escherichia coli.

       

      Oh, Min-Kyu , Lars Rohlin, Katy C. Kao, and James C. Liao. Global Expression Profiling of Acetate-grown Escherichia coli. J. Biol. Chem., Apr 2002; 277: 13175 – 13183.

      Gene expression profile differences in high and low metastatic human ovarian cancer cell lines by gene chip

       

      Xu S, Mou H, Lu G, Zhu C, Yang Z, Gao Y, Lou H, Liu X, Cheng Y, Yang W. Gene expression profile differences in high and low metastatic human ovarian cancer cell lines by gene chip. Chin Med J (Engl). 2002 Jan; 115(1): 36-41. PMID: 11930655 [PubMed – indexed for MEDLINE]

      Microarray Image Processing and Quality Control, in DNA Array Image Analysis Nuts & Bolts

       

      Petrov, A., Shah, S., Draghici, S.,Shams, S. , Microarray Image Processing and Quality Control, in DNA Array Image Analysis Nuts & Bolts, G. Kamberova, S. Shah (ed.), Ch. 6, DNA Press (2002)

      Data Analysis and Visualization in DNA Microarrays,Introduction to Bioinformatics

       

      Draghici, S. Data Analysis and Visualization in DNA Microarrays,Introduction to Bioinformatics, S.Krawetz and D. Womble (Eds.), Humana Press, 2002.

      Investigation of genotyping HLA DRB1 gene using oligoneucleotide arrays

       

      Chen JN, Li Y, Li YL, Qin HY, Li RY, Cao HM, Xie Y, Mao YM. [Investigation of genotyping HLA DRB1 gene using oligoneucleotide arrays] Yi Chuan Xue Bao. 2001; 28(10): 887-94. Chinese. PMID: 11695259 [PubMed – indexed for MEDLINE]

      Query Tools for Microarray Data Mining Applications

       

      Groch, K., Kuklin A. Query Tools for Microarray Data Mining Applications. Lab Technology. PharmaGenomics pp 53-55, August, 2001.

      Dna microarray analysis of cyanobacterial gene expression during acclimation to high light.

       

      Hihara Y, Kamei A, Kanehisa M, Kaplan A, Ikeuchi M. Dna microarray analysis of cyanobacterial gene expression during acclimation to high light. Plant Cell. 2001 Apr;13(4):793-806.

      DNA Arrays: The Steam Engine of the 21st Century?

       

      Draghici, S. DNA Arrays: The Steam Engine of the 21st Century?, ACM SIGBIO Newsletter, vol. 21, no. 1, pp. 2-9, April, 2001.

      Identification of differentially expressed genes in hepatocellular carcinoma with cDNA microarrays

       

      Shirota Y, Kaneko S, Honda M, Kawai HF, Kobayashi K. Identification of differentially expressed genes in hepatocellular carcinoma with cDNA microarrays. Hepatology ;33(4):832-40, April 2001.

      Quality Control in Mircroarray Image Analysis

       

      Kuklin, A., Petrov A., Shams, S. Quality Control in Mircroarray Image Analysis. Imaging & Microscopy Research, Development, Production. GIT Volume 1, April, 2001.

      Differential gene expression between chronic hepatitis B and C hepatic lesion

       

      Honda M, Kaneko S, Kawai H, Shirota Y, Kobayashi K. Differential gene expression between chronic hepatitis B and C hepatic lesion. Gastroenterology ;120(4):955-66, March 2001.

      alpha-fetoprotein-producing hepatoma cell lines share common expression profiles of genes in various categories demonstrated by cDNA microarray analysis

       

      Kawai HF, Kaneko S, Honda M, Shirota Y, Kobayashi K. alpha-fetoprotein-producing hepatoma cell lines share common expression profiles of genes in various categories demonstrated by cDNA microarray analysis. Hepatology ;33(3):676-91, March 2001.

      Gene Expression Pattern Analysis with Clustering in the Data Mining System GeneSight

       

      Hoff B., Kuklin, A., Shams, A. Gene Expression Pattern Analysis with Clustering in the Data Mining System GeneSight. BIOforum, International Life Sciences and Technology, February, 2001, Advanced Publication.

      Quantitative assessment of DNA microarrays–comparison with Northern blot analyses

       

      Taniguchi M, Miura K, Iwao H, Yamanaka S. Quantitative assessment of DNA microarrays–comparison with Northern blot analyses. Genomics. 2001 Jan 1;71(1):34-9.

      Experimental Design, Analysis of Variance and Slide Quality Assessment in Gene Expression Arrays

       

      Draghici, S., Kuklin A., Hoff, B., Shams S. Experimental Design, Analysis of Variance and Slide Quality Assessment in Gene Expression Arrays, Current Opinion in Drug Discovery & Development, vol. 4, no. 3, 2001.

      Data management in Microarray Fabrication, Image Processing, and Data Mining

       

      Kuklin, A., S. Shah, B. Hoff, and S. Shams. (2001) Data management in Microarray Fabrication, Image Processing, and Data Mining. In: Grigorenko (Ed.) DNA Arrays – Technologies and Experimental Strategies. CRC Press, Boca Raton pp. 115-128.

      DNA Microarray Production, Virtual Experimental Design, Databasing and Clone Tracking with CloneTracker

       

      Kuklin, A. DNA Microarray Production, Virtual Experimental Design, Databasing and Clone Tracking with CloneTracker. SC&I Technology Notes, January 2001.

      Automation in Microarray Image Analysis with AutoGene Technical Report

       

      Kuklin A., Shams S., Shah S. Automation in Microarray Image Analysis with AutoGene Technical Report, JALA Vol 5, No. 5, pp. 67-70, November, 2000.

      Information Processing Issues and Solutions Associated with Microarray Technology

       

      Kuklin, A., Shah, S., Hoff, B, Shams, S., Information Processing Issues and Solutions Associated with Microarray Technology. LRA, Vol 12,pp.317-327, September 2000.

      recent advances and applications in gene expression profiling

       

      Kawai H, Kaneko S. DNA chip; recent advances and applications in gene expression profiling. Tanpakushitsu Kakusan Koso ;45(11):1841-7. Review. Japanese. No abstract available, August 2000.

      The Transcriptional Response of Yeast to Saline Stress

       

      Posas, Francesc , James R. Chambers, John A. Heyman, James P. Hoeffler, Eulalia de Nadal, and Joaquín Ariño. The Transcriptional Response of Yeast to Saline Stress. J. Biol. Chem., Jun 2000; 275: 17249 – 17255.

      Spot Checks

       

      Kuklin, A. Spot Checks. Modern Drug Discovery pp 52-54. May, 2000.

      Laboratory Automation in Microarray Image Processing

       

      Kuklin, A. Laboratory Automation in Microarray Image Processing. International Laboratory pp 36-40. May, 2000.

      Data Mining in the Exploration of Genomic Expression.

       

      Shams, S., Kuklin, A. Data Mining in the Exploration of Genomic Expression. Bio/Medical Synergies. 22: 4-5 Summer 2000.

      That’s The Spot!

       

      That’s The Spot! The Scientist, Lab Consumer, Vol 14:5 March 6, 2000.

      Automation In Microarray Image Processing and Data Mining

       

      Kuklin, A. Automation In Microarray Image Processing and Data Mining. High Throughput Screening Supplement, BioMedical Products 1:4-8. 2000.

      Information Processing Issues and Solutions Associated with Microarray Technology

       

      Zhout, Y-X., Kalocsai, P., Chen, J-Y., and Shams, S. Information Processing Issues and Solutions Associated with Microarray Technology. Microarray Biochip Technology. Schena, M. (Ed.), Eaton Publishing, BioTechniques Books,. Natick, MA, U.S.A. pp. 167-200, 2000.

      High Throughput Screening of Gene Expression Signatures

       

      Shah, S., Kuklin, A., Shams, S. High Throughput Screening of Gene Expression Signatures. Genetica 108: 41-46, 2000.

      Sensitive Detection System for High- Density Microarrays Using Dendrimer Technology

       

      Stears, R.L., Getts, R.C., and Gullans, S.R. A Novel, Sensitive Detection System for High- Density Microarrays Using Dendrimer Technology. Physiol. Genomics 3:93-99, 2000.

      Exploring Expression Data: Identification and Analysis of Co-Expressed Genes.

       

      Heyer, L.J., Kruglyak, S., and Yooseph, S. Exploring Expression Data: Identification and Analysis of Co-Expressed Genes. Genome Research 9:1106-1115. 1999.

      Image Analysis and Data Management Issues Associated with Microarray Technology.

       

      Shams, S., Park, J.D., Chen, J.Y., Kalocsai, P. and Zhou, Y.X. Image Analysis and Data Management Issues Associated with Microarray Technology. DNA Microarrays – The New Frontier in Gene Discovery and Gene Expression Analysis. Short Course Syllabus. Society for Neuroscience, Miami Beach, FL. pp. 43-56, 1999.

      Gene Expression Profiles of Laser-Captured Adjacent Neuronal Subtypes

       

      Luo, L., Salunga, R., Guo, H. et al. Gene Expression Profiles of Laser-Captured Adjacent Neuronal Subtypes. Nature Medicine, Vol. 5 No.1: pp117-122. 1999.

      Visualization and Analysis of Gene Expression Data

       

      Kaloscai, P. and Shams, S. Visualization and Analysis of Gene Expression Data. JALA Vol 4, No. 5:pp17-21. 1999.

      Using Laser Capture Microdissection and cDNA Microarrays to Profile Expression Neuronal Subtypes

       

      Erlander, M. Using Laser Capture Microdissection and cDNA Microarrays to Profile Expression Neuronal Subtypes. DNA Microarrays. The New Frontier in Gene Discovery and Gene Expression Analysis. Short Course Syllabus. Society for Neuroscience, Miami Beach, FL. pp. 67- 71, 1999.