The most comprehensive and up-to-date solution for cytogenetics and molecular genetics in one system for analysis and interpretation of all genomic variants from microarray and NGS data.

Features and Benefits

Increase the efficiency of your case review using the new Variant Details Tab
Integrated automated ACMG CNV interpretation scoreboard
One-click Uniparental Disomy (UPD) detection, visualization, and reporting
Create your own bespoke Knowledgebase to store variant and genomic region information
Build and utilize genome-wide CNV and AOH profiles for different cancer types to assist in tumor diagnosis and interpretation
Don't leave past data behind - Automatic In-house case history & integrated genetic databases
Different platforms? NxClinical can do it all
Multi-user system with audit trail and global accessibility
Security - Maintains data quality and integrity
Speed to Decision - Faster TAT with automation, AI, and variant prioritization tools
Increase clinical utility and diagnostic yield
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Why NxClinical?


First step is to detect the CNVs. You can’t diagnose what you can’t see. NxClinical is the gold standard for calling CNVs from NGS and microarray data generated on any platform.




Context is everything! NxClinical provides integrated analysis and raw data visualization of CNV, SeqVar, and AOH simultaneously, on the same screen for each patient sample.




Make the right call in record time. AI driven tools and extensive automation for rapid and accurate interpretation. Active links to the latest databases keep your knowledge base fresh and up-to-date.



Dr. Karine Hovanes, PhD, FACMG

Vice President of Scientific Advancement and Laboratory Director, Invitae

Adoption of the NxClinical software has provided an efficient and secure workflow for our data batch loading and processing at our high volume clinical laboratory.


Dr. Sharon Mexal

Senior Director of Clinical Operations, Ambry Genetics

We were eager to be part of the Early Access program and try out NxClinical. We have now been using NxClinical for many years and each release has features that we find really useful. BioDiscovery has also been very receptive to feedback from us on feature requests and we are happy to see many of those implemented as they make our interpretation process even easier.


Todd Ackely

Manager, Michigan Molecular Genetics Laboratory (MMGL)

My CAP/CLIA clinical lab has used BioDiscovery CNV software since 2012. I have evaluated many CNV analysis software programs and the BioDiscovery software always has been the best choice for my lab. BioDiscovery listens to their customers and utilizes this information to improve and refine their software for clinical laboratories.


Liqiang Song

Be Creative Lab

NxClinical software allows us to comprehensively analyze CNV,LOH and sequence variants together. The local database functionality has provided a lot of valuable experience for us. We can directly access up-to-date integrated database within NxClinical software and add tracks to the genome browser for clinical analysis requirements.


Dr. Sarah Murray

Director of Genomics Technologies, UC San Diego

At the UCSD clinical genetics lab, we are tasked with providing a complete and clinically actionable genomic profile of a patient’s tumor. NxClinical allows us to do this rapidly and comprehensively by allowing us to consider CNV, LOH, and sequence variants together within a single software.


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These products empower Biologists and Geneticists with sophisticated, yet highly usable tools to analyze and interpret their data and draw meaningful conclusions.

*This software is for research use only. It is designed to assist clinicians and it is not intended as a primary diagnostic tool. It is each lab’s responsibility to use the software in accordance with internal policies as well as in compliance with applicable regulations.

*NxClinical uses the Human Phenotype Ontology. Find out more at

*This database/product contains information obtained from the Online Mendelian Inheritance in Man® (OMIM®) database, which has been obtained through a license from the Johns Hopkins University, which owns the copyright thereto.